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What must be documented on a drug administration record for vaccination by any method?

  1. Patient's fear level

  2. Manufacturer and lot number of the drug

  3. Patient's preference for the vaccination site

  4. Weather conditions

The correct answer is: Manufacturer and lot number of the drug

The drug administration record for vaccination by any method must document the manufacturer and lot number of the drug being administered. This information is important for tracking and identifying the specific vaccine that was given and for any potential recalls or adverse reactions. The other options provided are not necessary to document as they do not pertain to the administration of the vaccine. A patient's fear level, preference for vaccination site, and weather conditions do not impact the proper administration of the vaccine and therefore do not need to be recorded on the drug administration record.